Base Stacking In DNA | Base Stacking Interactions | What Is Base Stacking | Stability Of DNA | - 이중 자막
Hello friends, welcome to BMS learning.
In this video, I am to talk about base tagging in DNI.
First of all, I will tell you the general meaning of tagging.
That is, what does it mean when few things are tagged?
So it's simply a way of arranging things and the arrangement style says that one
thing is placed over the another or you can see one item is laid on top of the
other as you can see in the diagram.
Here one plate is on top of the other.
and this can be in this pattern also.
Now, what this tagging has to do with the DNA?
Well, it's found in DNA structure and is very important of property as it gives stability to DNA.
Now let's do this tagging in DNA itself.
So we have this double standard DNA formed of two strands running in opposite directions.
We know the DNA is made up of nucleotides and nucleotides in turn are made up of bases.
These tiny lines are representing bases.
To make things easy, I'm not showing the four straight groups in this diagram.
So there are a number of bases in DNA molecule.
If you see clearly, you can notice one base is on top of the other.
And this kind of arrangement is nothing but base stacking in DNA.
bases are tagged upon each other.
Now the question is, how this base tagging is important?
So we have two strands of DNA,
and they are connected to each other with the help of these hydrogen bombs, which are joining two bases from two anti-parallel strands.
This molding is crucial for the stability of DNA.
But apart from this, there are other interactions in DNA structure, which are very significant for DNA stability.
And those interactions are called, Stagging interaction.
And these tagging interactions are provided by stacked bases.
You can observe them here.
These are the two bases tagged on each other.
This tagging is possible because of these tagging interactions made between the two bases.
Let's know something more about base tagging.
Base tagging is much more prevalent in double strength than in single strength.
The base tagging interactions are hydrophobic and electrostatic in nature.
Major forces are hydrophobic interactions and vulnerable forces.
In nucleic acids, these instructions can be interesting and interesting in nature.
That means they are present both within a single strand and between the two strands.
Base tagging interactions increase with increasing soul concentration.
That's because.
High-solved concentrations mask the destabilizing, charge the position between the two negatively charged force-flow dash to the back ones.
This was all.
Thanks
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